About Sapien Labs

Evidence from data,
not recruited patients.

We build trial-grade external control arms from real-world clinical data. The evidence comes from records patients already generated in care, not from patients recruited to sit in a control arm.

01The thesis

One engine, benchmarked in the hardest place first.

Most trials still recruit a full control arm. That is slow, expensive, and often asks patients to take a placebo when the answer already exists in clinical records. We turn those real-world records into a defensible external control arm.

We benchmarked the method in psychiatry, where outcomes live in therapy notes and clinical narratives, not structured fields, and the endpoints are subjective. Deriving validated, traceable scales from that unstructured text is the hardest version of this problem. Because we started with the hardest version, the same engine extends across oncology, rare disease, neurology, immunology, and cardiometabolic.

We are one engine for every therapeutic area, with psychiatry as the first wedge. Not a psychiatry company, and not a claim of live cohorts everywhere. What we stand behind is traceability, validation against ground truth, and restraint.

02Team

The founders.

Shashank Choudhary

Shashank Choudhary

Cofounder and CEO
Aakash Bhagat

Aakash Bhagat

Cofounder and CTO
Advisors

Advised by senior leaders in clinical safety, biostatistics and psychiatry, including experts affiliated with Tufts and Johns Hopkins.

03Backers

Backed by Lightspeed.

With Entrepreneurs First and Transpose Platform. Selected into Lightspeed's India Ascends 2026 cohort.

  • Lightspeed
  • Entrepreneurs First
  • Transpose Platform

Talk to the people
building it.

Whether you run trials or hold the data, you reach the same small team. No layers.

San FranciscoFloors 1 and 2501 Folsom StSan Francisco, CA 94105shashank@sapienlabs.bio